It’s associated, not causal, and likely explained by diabetes as a 3rd variable. (Diabetes can blind you and glp-1 drugs are treatments for diabetes.)

The blindness is linked to rapidly changing A1C in diabetics and is a small increase in overall risk.

If you're just using it for weight loss and aren't diabetic, you have no increase in risk.

This is also why your weight loss should be monitored by a doctor.

Super uncertain, and, if the effect exists, it's tiny --- huge numbers of people have been taking these drugs for many years. Meanwhile, we know with certainty that T2D can blind you, and we know mechanistically why that happens. If you're at T2D risk, NAION would be a really dumb reason to avoid GLP-1s.