> Information here means the sequence of the amino acid residues, or other sequences related to it.
Prions do not transfer sequence information between proteins, so this is in keeping with Crick's idea.
I've always assumed that Watson understood Crick's idea perfectly well, but used the simpler formulation because it was easier to communicate, while still being mostly accurate.
Yes, that is highly likely. Most causality flows in the same direct—from DNA variants through RNA variants, through protein variance to differences in phenotypes.
Many many exceptions, but this is the main causal flow.
> Information here means the sequence of the amino acid residues, or other sequences related to it.
Prions do not transfer sequence information between proteins, so this is in keeping with Crick's idea.
I've always assumed that Watson understood Crick's idea perfectly well, but used the simpler formulation because it was easier to communicate, while still being mostly accurate.