Profiling in Python isn't hard either. But yeah, you really can't gain the performance of statically typed language in pure python (well, maybe with pypy). However, pushing the critical path into C library doesn't have to be as horrible as it sounds (for python developer at least). Cython[1] project can be very helpful. You just annotate critical variables/functions with types and compile the now cython code into C. This C code will be pure C as you wrote it in your typed parts, and bunch of ugly (but commented) calling of Python libraries in pure python parts. Then you just throw it at gcc and you are done. The best thing is that you can mix the typed/untyped code and pass variables around as it was pure python. Example from docs: http://docs.cython.org/src/userguide/tutorial.html#primes

1. http://cython.org/