Compare it with how you feel when you are on holidays. If there's a noticeable difference (not having muscle micro spasms, better sleep - or very tired just when you start them -, better breathing, more inspired or willing to try new things, etc) then you should reconsider to reduce the amount of stress/work in your life.
Holi-what? People on the path to burnout are usually the ones trying to push away time off. 'I'll rest when this is finished' - narrator: it never ended, the exceptional became nominal...