I remember trying to use this when I did an undergrad math course. My tutor went on about latex and such, I remember being very confused about the whole thing. Thus was prior to any knowledge on my part about markup languages or programming. I simply couldn't use it, I ended up using libreoffice with its equation editor. It worked for me at the time.

Now if I was doing something math related I'd probably try a combination of pandoc markdown with mathjax.