Honestly, the three-normal-buttons thumb cluster seems worse than the three-long-buttons in Moonlander. But would be nice to try it if i get the chance.
You press the key on or close to the the near edge using your thumb either way, so it really doesn't matter.
(This comment typed on an Ergodash: https://github.com/omkbd/ErgoDash It would be possible to press the key labelled with the noodle bowl using my thumb, although I'm not in the habit of doing so. I might try and make it a habit, now I think about it. The top half of the "Enter" on the right side is pointless; my keyboard has 2 small keys instead of the large one.)